Click for Miklossy's commentary on
Spirochetes and Alzheimer's
Click here for images
Alzheimer's
Disease
Round
areas of
Injury in
brain tissue
are called
Plaques
click here
to see
Alzheimer
plaques
BRASILIAN  
LYME  LIKE
ILLNESS
2 articles from
Dr Yoshinari
Click here for
article  ONE

Click here  for
Article TWO

Note: pictures
of an Erythema
migrans like
lesion are
presented.
Spirochetes are
illustrated. The
species is yet to
be determined
and for more click here
Borrelia
DNA inside
of
Alzheimer
Plaques
Click here
Spirochetal  
Forms ( Cystic
and
Filamentous)insi
de nerve cells in
Alzheimer
Hippocampus
tissue
Click on the
Images
Treponema
Pallidum
Buds,
Granules,
and Cysts
as found in
Human
Syphilitic
Chancres
and seen in
Fixed
unstained
smears
observed
under dark
ground
illumination
Coutts,
W.,E., and
Coutts,
W.R.
American
Journal of
Syphilis,
Gonorrhea
and
Venereal
Dis
37: 29-36,
1953
This
Landmark
Article from
Drs Coutts in
1952
describes
Cystic
forms of
Treponema
pallidum, with
Buds and
Granular
forms in
serum taken
from Syphilitic
Chancres.
The authors
survey the
previous
literature
dating back to
Schaudinn
and Hoffman,
and cite the
views of many
other
distinguished
syphilologists
endorsed the
view that
Pathogenic
spirochetes
have a
complex
life cycle
which
includes
vegetative (
spiral) and
diverse cystic
and granular
forms.

To View
Coutts
Article Click
here      
Stari Illness
Dr Ed Masters
Clinical photos
of Erythema Migrans
and Micrographs of
the Spirochetes
Click here to read
original article
Compariso
n of
Alzheimer
disease
Round
Plaques
with
Tertiary
Syphilis
Infection
of human
Brain with
Round
Plaques
Identical to
Alzheimer
Round
plaques
Click here
to See
Round
Plaques in
Syphilis
Brain
Video of
Alzheimer
's due
to
Infection
Click
here to
view
Video
Click here for Transfection Click here for 1995
Publication describing Borrelia DNA transfected to
Human chromosome 11qpublication
Syphilis
Plaques
Match
Alzheimer
plaques
slick
here
Both
plaques in
Brain are
caused by
Spirochetal
infection
click for PCR primers and Products from
Alzheimer brain
Round areas
of brain injury [
Click here to
see images]
are called
Plaques in two
Dementia
conditions
1. Alzheimer's
disease
2. Syphilis (
General
Paresis)
Rounded
profiles of
Spirochetes
(i.e.) CYSTIC
forms cause
the Plaques
Website Statement of Purpose
Why are there so many
Images and So Little Text ??
Click Here to Read Statement
MANY
PROFILES OF
BORRELIA CLICK
HERE
TO SEE ATLAS
Infectious
Alzheimer's -
Discussion of
evidence from
Animal
inoculation
studies
Nature
magazine
November
2006
Click
here for link to
the article
Spirochetes inside
of nerve cells
Harvard McLean
Hospital Brain
Bank tissue
Images - used in
Molecular
Interrogation
study for DNA of
Borrelia          
Alzheimer Disease
hippocampal
Click her
e
Images
of
Borrelia
Spirochet
es
cultured
from
Alzheimer
autopsy
brain  
[[ 1
IMAGE]]
Lyme disease
in Spinal fluid
at Stony Brook
Med Ctr
followed 8
years later by
death from
Alzheimer's -
case study
Borrelia and
Alzheimer's
disease Lecture
With all
powerpoint
slides
-Philadelphia
2005 ILADS
National
Scientific
Meeting -Click
HERE  
Powerpoint
slide show - 72
images
"Borrelia and
Dementia, Medical
Hypothesis"
Columbia LDA National
Scientific Meeting,
Philadelphia , Penn
October 20, 2006
Images - Click here -
Adobe format
Analysis of Pathology of
Alzheimer's disease under the
microscope - with connections
established to DNA of Borrelia
burgdorferi Flagellin DNA -
Specifically staining Alzheimer
plaques and GVB of
Alzheimer's hippocampal
neurons. Neurofibrillary
Tangles derived from
intraneuronal infection by
Borrelia in the model of SSPE
dementia with Alzheimer's
tangles in a childhood viral
infection dementia.
Cystic Borrelia - Compare Dr Brorson's Cyst forms with internal Filaments with Drs Alban and Nelson's
Paper #5
Medical
Hypotheses
--
Alzheimer's
Neuroborreliosi
s with Trans
synaptic
Spread of  
Infection and
Neurofibrillary
tangles derived
from
intraneuronal
spirochetes
Click here for
Abstract
"invasion of
human neuronal
and glial cells by
an infectious
Strain of Borrelia
burgdorferi
Microbes and
Infection
In press Sept
2006
Images of
infected cells
with Annotations
- Click here
Cystic borrelia in Alzheimer Autopsy Brain tissues
Click in image to see discussion of Spirochetal hieroglyphics and to see more spirochetes cultured from Alzheimer brain tissue
Cysts, Granular forms and corkscrew forms are examples of a spirochetal life cycle
Trans-synaptic
transmission of
Neuroborreliosis-
Related
articles -
Results of Pubmed
Search--------Click
here
The file contains
embedded links for
each of the listed
articles - just touch
the  Author's name
with your mouse
cursor  above the Title
of the article  -and
Click =to read the
Pubmed abstract
Dr Warthin ( inventor of the
Warthin Starry silver stain for
spirochetes) Professor Univ of
Michigan Med School All of the
variations of Spirochetes
demonstrated - EXCEPT - Cyst
forms are not in this TABLE
Double Click to see
Enlarged Warthin
Grid
Biofilms of
Borrelia
burgdorferi
Lecture -
Click Here
for Lecture
and images

July 7,2008
University
of New
Haven
Click here
Alzheimer/Borrelia Molecular
Interrogation project 1985
Quality controls and
experimental protocol

Agarose Gel Electrophoresis
of PCR products
DNA extracts - fresh Alzheimer
disease autopsy Hippocampus
slices obtained from Harvard
Medical School McLean Hospital
Brain Bank
Thank you very much for visiting
this site

The Research support
has been provided by
Turn the Corner Foundation,
New York ,NY
and
St Catherine of Siena Medical Center,
Smithtown, New York
Dot like forms
of Malaria Parasites are called
Merozoites (see position #26)
These are the smallest form of
the
Malaria parasite- Note the
diverse
forms which malaria parasites
demonstrate - in a Life Cycle
In like manner
the diverse forms of
Borrelia spirochetes
Spiral/corkscrew, granular
dot,  Cysts and L forms
constitute a Life cycle
Granular (dotlike)
spirochetal
forms are the spirochetal
equivalent of Merozoites
Link to Medical
Hypotheses
Website
--Transfection DNA - first report of
Borrelia to Human Transfection with 7
patients showing Flagellin B DNA
inserts in Human Chromosome 11q
site
--Plaques of Alzheimer's derived from
Cysts of Borrelia by In Situ DNA
hybridization evidence
--Cyst forms of Borrelia as Unifying
concept for
Parkinson';s , ALS, Pick's, and other
Tauopathies
Click Here
Research papers (6)--Click here
Medical Hypotheses - Draft versions with images
obtain all 6 papers in one  PDF File
Lateral DNA Transfer Articles
and Monograph
lick here for review article

Click here for article on    
mechanisms of DNA transfer
Many Images presented on this
site-
are Copyright -  by
Other Authors , and other
Publishers
and by
Alan B. Macdonald MD
Borrelia Attack Models
Lecture May 19 2007
University of New Haven
Images from Powerpoint
Click Here to view
Cases 2,3,4,5,6,7
Links to NCBI database files
DQ188100.1
DQ188101.1
DQ188102.1
DQ188103.1
DQ188104.1
DQ188105.1
Click Here for Images
of Biofilms of Borrelia
burgdorferi
Biofilms of Borrelia
burgdorferi in human
tissue -An
Explanation of
microbial persistence
in the Human host >
Chronic Lyme
borreliosis is a biofilm
infection
Click here for Dr P.
Collart manuscript (in
French) illustration of
Granular and Cystic
forms of Treponema
Pallidum Biology of
syphilis
in French
Granular forms of Treponema
spirochetes are dot-like particles
which can regenerate the entire
corkscrew shaped forms
Click here to see granular forms
Bibliography of literature
on Cystic Forms of
Spirochetes - Click here
Granular forms of Treponema
spirochetes are dot-like particles
which can regenerate the entire
corkscrew shaped forms
Click here to see granular forms
Biofilms of Borrelia Burgdorferi
in Chronic Cutaneous
Borreliosis
American Journal of Clinical
Pathology 2008
Click here for full text
and graphics
2008 Paper -
"Persisting atypical and
cystic forms of
Borrelia
burgdorferi
and local
inflammation in Lyme
Neuroborreliosis"
Dr. Judith Miklossy and
colleagues
Granular forms of Treponema
spirochetes are dot-like particles
which can regenerate the entire
corkscrew shaped forms
Click here to see granular forms
Borrelia Cystic form---
DNA In Situ Hybridization
method for staining-
Autopsy Case study-

Diffuse Lewy body Dementia
--Click here to view
Concurrent Neocortical Borreliosis and
Alzheimer's disease - Human Pathology
1987
Concurrent Neocortical Borreliosis and
Alzheimer's disease - II- Demonstration
of a Spirochetal Cyst Form - Annals of
the New York Academy of Sciences
Click here
1987 and 1989 papers on
Concurrent Neocortical Borreliosis and
Alzheimer's
cell wall deficient
forms of Borrelia
burgdorferi
Click
here to see images
Discussion
of Cystic
Spirochetes as links
to
Pick bodies
Lewy bodies
ALS Spherical
Bodies
Alzheimer Plaque
s
Transfection (Lateral DNA transfer)
Borrelia to Human Alzheimer DNA
Data
link to index
click to link to page molecular_6